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make it out of the laboratory survive this tortuous process and reach the 
marketplace in the form of FDA-approved pharmaceuticals. . . .  Only 
patent protection can make the innovator's substantial investment in 
development and clinical testing economically rational. 
 
Jay Dratler, Jr., Alice in Wonderland Meets the U.S. Patent System, 38 Akron L. Rev. 
299, 313-14 (2005) (footnotes omitted). 
 Business 
method 
patents, unlike those granted for pharmaceuticals and other 
products, offer rewards that are grossly disproportionate to the costs of innovation.  In 
contrast to technological endeavors, business innovations frequently involve little or no 
investment in research and development.  Bilski, for example, likely spent only nominal 
sums to develop his hedging method.  The reward he could reap if his application were 
allowed—exclusive rights over methods of managing risks in a wide array of commodity 
transactions—vastly exceeds any costs he might have incurred in devising his 
“invention.” 
B.   
 
“[S]ometimes too much patent protection can impede rather than ‘promote the 
Progress of Science and useful Arts,’ the constitutional objective of patent and copyright 
protection.”  Lab. Corp. of Am. Holdings v. Metabolite Labs., Inc., 548 U.S. 124, 126 
(2006) (Breyer, J., joined by Stevens and Souter, JJ., dissenting from dismissal of writ 
of certiorari) (emphasis in original).  This is particularly true in the context of patents on 
methods of conducting business.  Instead of providing incentives to competitors to 
develop improved business techniques, business method patents remove building 
blocks of commercial innovation from the public domain.  Dreyfuss, supra at 275-77.  
Because they restrict competitors from using and improving upon patented business 
methods, such patents stifle innovation.  When “we grant rights to exclude 
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